Drug Interactions | 5 Tips You Should Do To Avoid Them



How Can I Avoid Reactions to Medications?

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I recently had quite a severe reaction (dizziness, racing heart, and confusion, as if I were drunk) to a lidocaine injection; I had to have a Benadryl injection to sort me out. Apparently, I am reacting to sulfites. Should I be wearing a bracelet, and should I be tested to find out what, specifically, I'm allergic to? My general practitioner is not inclined to send me to a specialist, and I am wondering what I should do to prevent this from happening again.

— Sue, Canada

Reactions to local anesthetics are relatively common and are usually not caused by the type of allergy that progresses to anaphylaxis (a life-threatening, whole-body allergic reaction); rather, they result from adverse reactions to the preservatives added to these medications or a heightened sensitivity to the desired effects of the anesthetic itself. This may be why your doctor said that you were probably reacting to sulfites (a common preservative) and didn't need a referral to a specialist.

There are a few simple things you can do to protect yourself from another reaction. First, find out exactly what preparation of lidocaine you reacted to. Was it drawn up from a multiuse vial? This is important because multiuse vials are the ones that typically contain the problematic preservatives. In contrast, small, single-use vials are often preservative-free because they are not intended to be stored after they are opened. Find out what preservatives were in the preparation you received, and make sure you aren't given such a preparation again.

You should also discuss the reaction you had with any physicians responsible for future procedures involving a local anesthetic, so that they can plan accordingly. Usually, the approach is to use a different local anesthetic and a preservative-free preparation.

You can ask any physician performing such a procedure to inject just a tiny amount of the anesthetic first, wait 20 minutes, and then inject the rest if you have no unusual symptoms. This would allow any symptoms to develop before you would have received a full dose.






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Date: 19.12.2018, 05:36 / Views: 43162